EDITOR’S NOTE: This entry is the first in a new and (hopefully) ongoing series to highlight new technology related to almond and tree nut production. The question/answer format is set to focus more on the technical aspects and application of the technology. Since we are approaching hull-split, I thought a reasonable place to start would be with Vestaron, a company which recently released a new class of insecticides.Thanks to Noel Cornejo for taking the time to answer my questions. Question (Q): Spear-Lep is a new group of insecticides that has been shown to be effective on lepidopteran pests, such as peach twig borer, codling moth, and navel orangeworm. What is the active ingredient and how does this product work? Answer (A): The active ingredient is an insecticidal peptide called GS-omega/kappa-Hxtx-Hv1a. It was carefully optimized to target the nicotinic acetylcholine receptor in the insect nervous system, but at a receptor site distinct from Spinosad and neonicotinoids. The end result is paralysis of the lepidopteran larvae that ingest it. Q. Is this product directly toxic to insect pests? Or does it have to be consumed? How is the activity on developing larvae (may have been answered above)? A. For lepidopteran pests Spear works through ingestion. Extensive studies confirm activity against neonates as well as later instars of all species tested to date. At high v/v concentrations, Spear works though topical contact against smaller, soft-bodied pests such as mites, thrips and whiteflies. Q. How is this product different from what is currently on the market and is there any efficacy data comparisons among the various products on the market?  A. This novel class of insecticidal peptide is the first of its kind. Identified in nature, and then optimized painstakingly in the lab, Vestaron’s peptide insecticides are designed to target neuromuscular receptors proven through